Epigenetics & Nuclear Signaling Antibodies 1

ASCC2 Rabbit Polyclonal Antibody (CAB13789)

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SKU:
CAB13789
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
p100, ASC1p100, ASCC2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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ASCC2 Antibody (CAB13789)

The ASCC2 Antibody (CAB13789) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to ASCC2 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential reagent for studies in cancer biology and genomic stability.ASCC2 is known to play a crucial role in the DNA damage response pathway, contributing to the repair of DNA lesions and ensuring the integrity of the genome.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ASCC2 Antibody
SKU:CAB13789
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LACL EYYH YDPE QVIN NILE ERLA PTLS QLDR NLDR EMKP DPTP LLTS RHNV FQND EFDV FSRD SVDL SRVH KGKS TRKE ENTR SLLN DKRA VAAQ RQRY EQYS VVVE EVPL QPGE SLPY HSVY YEDE YDDT YDGN QVGA NDAD SDDE LISR RPFT IPQV LRTK VPRE GQEE DDDD EEDD ADEE APKP DHFV QDPA VLRE KAEA RRMA FLAK KGYR HDSS TAVA GSPR GHGQ SRET TQER RKKE ANKA TRAN HNRR TMAD RKRS KGMI PS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:p100, ASC1p100, ASCC2
Positive Sample:HT-29, HepG2, A-431, HeLa, 293T, Mouse eye, Rat pancreas
Cellular Localization:Nuclear Speck, Nucleoplasm, Nucleus.
Calculated MW:86kDa
Observed MW:110kDa

Predicted to enable ubiquitin binding activity. Involved in regulation of transcription, DNA-templated; rescue of stalled ribosome; and ribosome-associated ubiquitin-dependent protein catabolic process. Located in nucleus. Part of activating signal cointegrator 1 complex.

Purification MethodAffinity purification
Gene ID84164
RRIDAB_2760647
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ASCC2 Rabbit pAb (CAB13789) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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