Immunology Antibodies 2

AKAP8 Rabbit Polyclonal Antibody (CAB3049)

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SKU:
CAB3049
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
AKAP-8, AKAP95, AKAP 95, AKAP-95, AKAP8
Research Use:
Immunology
Frequently bought together:

Description

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AKAP8 Antibody (CAB3049)

The AKAP8 Antibody (CAB3049) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and is highly specific to AKAP8 in human samples, making it suitable for applications such as Western blotting.AKAP8, also known as A-kinase anchor protein 8, is involved in various cellular processes, including cell growth, differentiation, and apoptosis. By targeting AKAP8 with this antibody, researchers can study its function in different cell types and gain insights into its potential role in disease mechanisms.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:AKAP8 Antibody
SKU:CAB3049
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:HCLA CDML IPAQ PQLL QRHL HSVD HNHN RRLA AEQF KKTS LHVA KSVL NNRH IVKM LEKY LKGE DPFT SETV DPEM EGDD NLGG EDKK ETPE EVAA DVLA EVIT AAVR AVDG EGAP APES SGEP AEDE GPTD TAEA GSDP QAEQ LLEE QVPC GTAH EKGV PKAR SEAA EAGN GAET MAAE AESA QTRV APAP AAAD AEVE QTDA ESKD AVPT E
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AKAP-8, AKAP95, AKAP 95, AKAP-95, AKAP8
Positive Sample:LO2, 293T, BxPC-3, HeLa, Jurkat, mouse thymus
Cellular Localization:Nucleus Matrix.
Calculated MW:76kDa
Observed MW:110kDa

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Purification MethodAffinity purification
Gene ID10270
RRIDAB_2764853
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using AKAP8 Rabbit pAb (CAB3049) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageConfocal immunofluorescence analysis of U2OS cells using AKAP8 Rabbit pAb (CAB3049) at dilution of 1:200. Blue: DAPI for nuclear staining.
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