YAP1 Polyclonal Antibody (CAB21333)

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SKU:
CAB21333
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:YAP1 Polyclonal Antibody
Product Code:CAB21333
Reactivity:Human, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:500-1:2000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location:Cytoplasm, Nucleus

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1).
Sequence:PTAQH LRQSS FEIPD DVPLP AGWEM AKTSS GQRYF LNHID QTTTW QDPRK AMLSQ MNVTA PTSPP VQQNM MNSAS GPLPD GWEQA MTQDG EIYYI NHKNK TTSWL DPRLD PRFAM NQRIS QSAPV KQPPP LAPQS PQGGV MGGSN SNQQQ QMRLQ QLQME KERLR LKQQE LLRQA MRNIN PSTAN SPKCQ ELALR SQLPT LEQDG GTQNP VSSPG MSQEL RTMTT NSSDP FLNSG TYHSR DESTD SGLSM SSYSV PRTPD DFLNS VDEMD TGDTI NQSTL PSQQN RFPDY LEAIP GTNVD LGTLE GDGMN IEGEE LMPSL QEALS SDILN DMESV LAATK LDKES FLTWL
Synonyms:YAP, YKI, COB1, YAP2, YAP-1, YAP65
Calculated MW:54kDa
Observed MW:Refer to figures
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