XAF1 Polyclonal Antibody
- SKU:
- CAB10685
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | XAF1 Polyclonal Antibody |
| Product Code: | CAB10685 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Mitochondrion, Nucleus |
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human XAF1 (NP_059993.2). |
| Sequence: | MEGDF SVCRN CKRHV VSANF TLHEA YCLRF LVLCP ECEEP VPKET MEEHC KLEHQ QVGCT MCQQS MQKSS LEFHK ANECQ ERPVE CKFCK LDMQL SKLEL HESYC GSRTE LCQGC GQFIM HRMLA QHRDV CRSEQ AQLGK GERIS APERE IYCHY CNQMI PENKY FHHMG KCCPD SEFKK HFPVG NPEIL PSSLP SQAAE NQTST MEKDV RPKTR SINRF PLHSE SSSKK APRSK NKTLD PLLMS EPKPR TSSPR GDKAA YDILR RCSQC GILLP LPILN QHQEK CRWLA SSKGK QVRNF S |
| Synonyms: | BIRC4BP, XIAPAF1, HSXIAPAF1 |
| Calculated MW: | 35kDa |
| Observed MW: | Refer to figures |
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