Tryptophanyl-tRNA synthetase 1 Monoclonal Antibody (CAB22440)

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SKU:
CAB22440
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
Synonyms:
HMN9, WARS, IFI53, IFP53, GAMMA-2, Tryptophanyl-tRNA synthetase 1
Frequently bought together:

Description

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Tryptophanyl-tRNA synthetase 1 Monoclonal Antibody (CAB22440)

The Tryptophanyl-tRNA synthetase 1 Monoclonal Antibody (CAB22440) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed specifically for human samples, is highly specific and sensitive, allowing for precise detection of the Tryptophanyl-tRNA Synthetase 1 protein in various biological samples.Tryptophanyl-tRNA Synthetase 1 is a key enzyme involved in the process of protein translation, specifically in the attachment of tryptophan to its corresponding tRNA molecule. Dysregulation of this enzyme has been linked to various diseases, including cancer and neurodegenerative disorders, making it a valuable target for research in these areas.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:Tryptophanyl-tRNA synthetase 1 Monoclonal Antibody
SKU:CAB22440
Size:20μL, 100μL
Reactivity:Human
Clone Number:ARC2687
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:VNKH AFSG GRDT IEEH RQFG GNCD VDVS FMYL TFFL EDDD KLEQ IRKD YTSG AMLT GELK KALI EVLQ PLIA EHQA RRKE VTDE IVKE FMTP RKLS FDFQ
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:1000 - 1:4000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HMN9, WARS, IFI53, IFP53, GAMMA-2, Tryptophanyl-tRNA synthetase 1
Positive Sample:U-937
Cellular Localization:Cytoplasm.
Calculated MW:53kDa
Observed MW:53kDa

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID7453
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from U-937 cells using Tryptophanyl-tRNA synthetase 1 Rabbit mAb (CAB22440) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human placenta using Tryptophanyl-tRNA synthetase 1 Rabbit mAb (CAB22440) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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