Description
| Product Name: | Tryptophanyl-tRNA synthetase 1 Monoclonal Antibody |
| Product Code: | CAB22440 |
| Reactivity: | Human |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2687 |
| Reactivity: | Human |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 372-471 of human Tryptophanyl-tRNA synthetase 1 (P23381). |
| Sequence: | VNKHA FSGGR DTIEE HRQFG GNCDV DVSFM YLTFF LEDDD KLEQI RKDYT SGAML TGELK KALIE VLQPL IAEHQ ARRKE VTDEI VKEFM TPRKL SFDFQ |
| Synonyms: | HMN9, WARS, IFI53, IFP53, GAMMA-2 |
| Calculated MW: | 53kDa |
| Observed MW: | Refer to figures |