TPMT Monoclonal Antibody [PAT2E7AT] (CPAB0109)

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SKU:
CPAB0109
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT2E7AT
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:TPMT Antibody
Product Sku:CPAB0109
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TPMT mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TPMT amino acids 1-245 purified from Ecoli.
Clone:PAT2E7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:TPMT antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.
Synonyms:TPMT, Thiopurine S-methyltransferase, EC 2.1.1.67, Thiopurine methyltransferase.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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