TMED10 Polyclonal Antibody
- SKU:
- CAB21344
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IHC
Description
| Product Name: | TMED10 Polyclonal Antibody |
| Product Code: | CAB21344 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus, Melanosome, Single-pass type I membrane protein, cis-Golgi network membrane, secretory vesicle membrane, trans-Golgi network membrane |
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3). |
| Sequence: | HLPIN SRKCL REEIH KDLLV TGAYE ISDQS GGAGG LRSHL KITDS AGHIL YSKED ATKGK FAFTT EDYDM FEVCF ESKGT GRIPD QLVIL DMKHG VEAKN YEEIA KVEKL KPLEV ELRRL EDLSE SIVND FAYMK KREEE MRDTN ESTNT RVLYF S |
| Synonyms: | p23, TMP21, p24d1, S31I125, Tmp-21-I, S31III125, P24(DELTA) |
| Calculated MW: | 25kDa |
| Observed MW: | Refer to figures |
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