Description
Antibody Name: | TMBIM4 Antibody |
Antibody SKU: | PACO04561 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Rat |
Immunogen: | synthesized peptide derived from the Internal region of human GAAP. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | TMBIM4; GAAP; LFG4; CGI-119; Protein lifeguard 4; Golgi anti-apoptotic protein; Protein S1R; Transmembrane BAX inhibitor motif-containing protein 4; Z-protein |
UniProt Protein Function: | TMBIM4: Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release. Belongs to the BI1 family. LFG subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 12q14.3Cellular Component: Golgi membrane; Golgi stack; integral to membraneMolecular Function: protein bindingBiological Process: apoptosis; negative regulation of apoptosis; regulation of calcium-mediated signaling |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9HC24 |
NCBI GenInfo Identifier: | 322510100 |
NCBI Gene ID: | 51643 |
NCBI Accession: | Q9HC24.3 |
UniProt Secondary Accession: | Q9HC24,Q542Z6, Q9UHY5, Q9Y3C2 |
UniProt Related Accession: | Q9HC24 |
Molecular Weight: | 26,971 Da |
NCBI Full Name: | Protein lifeguard 4 |
NCBI Synonym Full Names: | transmembrane BAX inhibitor motif containing 4 |
NCBI Official Symbol: | TMBIM4 |
NCBI Official Synonym Symbols: | S1R; GAAP; LFG4; ZPRO; CGI-119 |
NCBI Protein Information: | protein lifeguard 4 |
UniProt Protein Name: | Protein lifeguard 4 |
UniProt Synonym Protein Names: | Golgi anti-apoptotic protein; Protein S1R; Transmembrane BAX inhibitor motif-containing protein 4; Z-protein |
Protein Family: | Protein lifeguard |
UniProt Gene Name: | TMBIM4 |
UniProt Entry Name: | LFG4_HUMAN |