TIR1 Polyclonal Antibody
- SKU:
- CAB21276
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Plant - Arabidopsis
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TIR1 Polyclonal Antibody |
| Product Code: | CAB21276 |
| Reactivity: | Arabidopsis thaliana |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Arabidopsis thaliana |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Inflorescences |
| Cellular Location: | nucleus |
Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 495-594 of arabidopsis thaliana TIR1 (NP_567135.1). |
| Sequence: | DKALL ANASK LETMR SLWMS SCSVS FGACK LLGQK MPKLN VEVID ERGAP DSRPE SCPVE RVFIY RTVAG PRFDM PGFVW NMDQD STMRF SRQII TTNGL |
| Synonyms: | AtTIR1, TRANSPORT INHIBITOR RESPONSE 1 |
| Calculated MW: | 67kDa |
| Observed MW: | 67kDa |
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