Epigenetics & Nuclear Signaling Recombinant Proteins
Thymidylate Kinase/DTYMK Recombinant Protein (RPES0808)
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- SKU:
- RPES0808
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Description
system_update_altDatasheet
Thymidylate Kinase/DTYMK Recombinant Protein
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest that the cDNA codes for authentic human dTMP kinase. The mRNA levels and enzyme activities corresponded to cell cycle progression and cell growth stages.
| Product Name: | Thymidylate Kinase/DTYMK Recombinant Protein (RPES0808) |
| Product Code: | RPES0808 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Thymidylate kinase,dTMP kinase,DTYMK,CDC8, TMPK, TYMK |
| Accession: | P23919 |
| Sequence: | Met 1-Lys212 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Thymidylate kinase is produced by our Mammalian expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.9 kDa |
| AP Mol Mass: | 20 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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