Description
Product Name: | TET1 Polyclonal Antibody |
Product Code: | CAB21766 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | nucleoplasm, nucleus |
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 820-978 of mouse TET1 (NP_081660.1). |
Sequence: | GAEPT IFNNH PNTHS AGSRP HPPEK VPNKE PKDGS PVQPS LLSLM KDRRL TLEQV VAIEA LTQLS EAPSE SSSPS KPEKD EEAHQ KTASL LNSCK AILHS VRKDL QDPNV QGKGL HHDTV VFNGQ NRTFK SPDSF ATNQA LIKSQ GYPSS PTAEK KGAA |
Synonyms: | LCX, Cxxc6, mKIAA1676, D10Ertd17e, 2510010B09Rik |
Calculated MW: | 219kDa |
Observed MW: | Refer to figures |