Name: TBX15 Antibody (PACO38766)
SKU: PACO38766
Availability: OutOfStock

Antibody Name:	TBX15 Antibody (PACO38766)
Antibody SKU:	PACO38766
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:	Human
Immunogen:	Recombinant Human T-box transcription factor TBX15 protein (1-496AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot. All lanes: TBX15 antibody at 5µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 66, 55 kDa. Observed band size: 66 kDa.

Background:	Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes (By similarity).
Synonyms:	T-box transcription factor TBX15 (T-box protein 15) (T-box transcription factor TBX14) (T-box protein 14), TBX15, TBX14

UniProt Protein Function:	TBX15: Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes. Defects in TBX15 are the cause of Cousin syndrome (COUSS); also known as craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature. Cousin syndrome is defined as pelviscapular dysplasia with epiphyseal abnormalities, congenital dwarfism and facial dysmorphy (frontal bossing, hypertelorism, narrow palpebral fissures, deep set globes, strabismus, low-set posteriory rotated and unusually formed external ears, dysplasia of conchae, small chin, short neck with redundant skin folds, and a low hairline). Intelligence may vary from normal to moderately impaired. Radiographic features comprise aplasia of the body of the scapula, hypoplasia of the iliac bone, humeroradial synosthosis, dislocation of the femoral heads, and moderate brachydactyly. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1p11.1 Molecular Function:protein binding Disease: Cousin Syndrome
NCBI Summary:	This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
UniProt Code:	Q96SF7
NCBI GenInfo Identifier:	59803103
NCBI Gene ID:	6913
NCBI Accession:	Q96SF7.2
UniProt Secondary Accession:	Q96SF7,Q08E76, Q5JT54, Q5T9S7,
UniProt Related Accession:	Q96SF7
Molecular Weight:	54,671 Da
NCBI Full Name:	T-box transcription factor TBX15
NCBI Synonym Full Names:	T-box 15
NCBI Official Symbol:	TBX15
NCBI Official Synonym Symbols:	TBX14
NCBI Protein Information:	T-box transcription factor TBX15
UniProt Protein Name:	T-box transcription factor TBX15
UniProt Synonym Protein Names:	T-box transcription factor TBX14; T-box protein 14
Protein Family:	T-box transcription factor
UniProt Gene Name:	TBX15
UniProt Entry Name:	TBX15_HUMAN