SUMO2/3 Monoclonal Antibody [PAT10F1AT] (CPAB0433)
![SUMO2/3 Monoclonal Antibody [PAT10F1AT] (CPAB0433)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58655/63837/sumo23-monoclonal-antibody-pat10f1at-cpab0433__03919__88132.1706535173.jpg?c=1 "SUMO2/3 Monoclonal Antibody [PAT10F1AT] (CPAB0433)")
- SKU:
- CPAB0433
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT10F1AT
- Applications:
- WB
- Applications:
- IF
- Applications:
- ELISA
![SUMO2/3 Monoclonal Antibody [PAT10F1AT] (CPAB0433)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58655/63837/sumo23-monoclonal-antibody-pat10f1at-cpab0433__03919__88132.1706535173.jpg?c=1&imbypass=on "SUMO2/3 Monoclonal Antibody [PAT10F1AT] (CPAB0433)")
Description
system_update_alt Datasheet
| Product Name: | SUMO2/3 Antibody |
| Product Sku: | CPAB0433 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human SUMO2/3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SUMO2 amino acids 1-93 purified from Ecoli. |
| Clone: | PAT10F1AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, Immunofluorescence, ELISA |
| Purification Method: | SUMO2/3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | Small Ubiquitin-like Modifiers (SUMOs) are a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. Unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. All SUMO proteins share the conserved ubiquitin domain and the C-terminal diglycine cleavage/attachment site. Human SUMO2, also known as Sentrin2 and SMT3B is synthesized as a 95 amino acid (aa), 11 kDa propeptide that contains a two aa C-terminal prosegment, and an 18 aa N-terminal protein interacting region (aa 33 -50). Following prosegment cleavage, the C-terminal glycine is enzymatically attached to a lysine on a target protein. Human SUMO2 shares 100% sequence identity to SUMO-2 from mouse. SUMO2 also has very high sequence homology to SUMO3 and SUMO4, 86 % and 85%, respectivel |
| Synonyms: | Small ubiquitin-related modifier 2, SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, HSMT3, SUMO-3, SUMO2, SMT3B, SMT3H2, MGC117191. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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