SUMO2/3 Monoclonal Antibody
- SKU:
- CAB22734
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | SUMO2/3 Monoclonal Antibody |
| Product Code: | CAB22734 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57112 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, NIH/3T3, PC-12 |
| Cellular Location: | Nucleus, PML body |
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Immunogen: | Recombinant protein of human SUMO2/3. |
| Sequence: | MADEK PKEGV KTENN DHINL KVAGQ DGSVV QFKIK RHTPL SKLMK AYCER QGLSM RQIRF RFDGQ PINET DTPAQ LEMED EDTID VFQQQ TGGVY |
| Synonyms: | HSMT3, SMT3B, SUMO3, Smt3A, SMT3H2 |
| Calculated MW: | 11kDa |
| Observed MW: | 17kDa |
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