| Purification Method: | |
| Isotype: | IgG1 |
| Background: | STAT1 is a member of the Signal Transducers and Activators of Transcriptionfamily of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type Ior type IIinterferons. In response to IFN-?stimulation, STAT1 forms homodimers or heterodimers with STAT3that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element; in response to either IFN-? or IFN-?stimulation, STAT1 forms a heterodimer with STAT2that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case, binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes). |
| Synonyms: | Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1, ISGF-3, STAT91, DKFZp686B04100. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
![STAT1 Monoclonal Antibody [PAT1F4A] (CPAB0172)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58398/63580/stat1-monoclonal-antibody-pat1f4a-cpab0172__80123__03972.1706534997.jpg?c=1 "STAT1 Monoclonal Antibody [PAT1F4A] (CPAB0172)")
![STAT1 Monoclonal Antibody [PAT1F4A] (CPAB0172)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58398/63580/stat1-monoclonal-antibody-pat1f4a-cpab0172__80123__03972.1706534997.jpg?c=1&imbypass=on "STAT1 Monoclonal Antibody [PAT1F4A] (CPAB0172)")
