SPHK1/Sphingosine Kinase 1 Recombinant Protein (RPES0654)

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SKU:
RPES0654
Product Type:
Recombinant Protein
Species:
Human

Description

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SPHK1/Sphingosine Kinase 1 Recombinant Protein

SPHK1; also known as sphingosine Kinase 1; catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation; survival; migration; cytoskeletal organization; and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory; antiapoptotic; and immune processes.

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