Description
Product Name: | SOD2 Polyclonal Antibody |
Product Code: | CAB21805 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Mitochondrion matrix |
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2). |
Sequence: | KHSLP DLPYD YGALE PHINA QIMQL HHSKH HAAYV NNLNV TEEKY QEALA KGDVT AQIAL QPALK FNGGG HINHS IFWTN LSPNG GGEPK GELLE AIKRD FGSFD KFKEK LTAAS VGVQG SGWGW LGFNK ERGHL QIAAC PNQDP LQGTT GLIPL LGIDV WEHAY YLQYK NVRPD YLKAI WNVIN WENVT ERYMA CKK |
Synonyms: | GC1, IPOB, IPO-B, MNSOD, MVCD6, GClnc1, Mn-SOD |
Calculated MW: | 25kDa |
Observed MW: | Refer to figures |