SNCA [PAT1E10A] (CPAB0573)
![SNCA [PAT1E10A] (CPAB0573)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58794/63976/snca-pat1e10a-cpab0573__44463__26033.1706535219.jpg?c=1 "SNCA [PAT1E10A] (CPAB0573)")
- SKU:
- CPAB0573
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
![SNCA [PAT1E10A] (CPAB0573)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58794/63976/snca-pat1e10a-cpab0573__44463__26033.1706535219.jpg?c=1&imbypass=on "SNCA [PAT1E10A] (CPAB0573)")
Description
system_update_alt Datasheet
| Product Name: | SNCA (1-140) Antibody |
| Product Sku: | CPAB0573 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human SNCA mAb, clone PAT1E1A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SNCA protein 1-14 amino acids purified from Ecoli. |
| Clone: | PAT1E10A. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | SNCA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | a-Synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has been suggested to be implicated in the pathogenesis of Parkinsons disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that a-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140). |
| Synonyms: | Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, PD1, PARK1, PARK4, MGC110988, a-Synuclein, SNCA. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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