Description
system_update_alt Datasheet
Product Name: | SNAP25 Antibody |
Product Sku: | CPAB0521 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human SNAP25 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SNAP25 amino acids 1-26 purified from Ecoli. |
Clone: | P4E11AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | SNAP25 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters. |
Synonyms: | Super-Protein, SUP, RIC4, SEC9, SNAP, RIC-4, SNAP25, SNAP-25, Synaptosomal-associated protein 25, Synaptosomal-associated 25 kDa protein, FLJ23079, bA416N4.2, dJ1068F16.2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |