Description
| Product Name: | SMARCAD1 Polyclonal Antibody |
| Product Code: | CAB24882 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | U-2 OS, Jurkat, 293T |
| Cellular Location: | Chromosome, Nucleus |
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 928-1026 of human SMARCAD1(NP_064544.2). |
| Sequence: | STKAG GLGIN LTSAN VVILH DIDCN PYNDK QAEDR CHRVG QTKEV LVIKL ISQGT IEESM LKINQ QKLKL EQDMT TVDEG DEGSM PADIA TLLKT SMGL |
| Synonyms: | SMARCAD1, ADERM, BASNS, ETL1, HEL1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 |
| Calculated MW: | 68kDa/117kDa |
| Observed MW: | 150kDa |