Description
Product Name: | SKIV2L Polyclonal Antibody |
Product Code: | CAB10657 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SKIV2L (NP_008860.4). |
Sequence: | MMETE RLVLP PPDPL DLPLR AVELG CTGHW ELLNL PGAPE SSLPH GLPPC APDLQ QEAEQ LFLSS PAWLP LHGVE HSARK WQRKT DPWSL LAVLG APVPS DLQAQ RHPTT GQILG YKEVL LENTN LSATT SLSLR RPPGP |
Synonyms: | HLP, 170A, SKI2, DDX13, SKI2W, SKIV2, THES2, SKIV2L, SKIV2L1 |
Calculated MW: | 138kDa |
Observed MW: | Refer to figures |