SHMT2 Polyclonal Antibody
- SKU:
- CAB21803
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | SHMT2 Polyclonal Antibody |
| Product Code: | CAB21803 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:100, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | SW620 |
| Cellular Location: | Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, mitochondrion nucleoid |
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-504 of human SHMT2 (NP_005403.2). |
| Sequence: | PSPFK HADIV TTTTH KTLRG ARSGL IFYRK GVKAV DPKTG REIPY TFEDR INFAV FPSLQ GGPHN HAIAA VAVAL KQACT PMFRE YSLQV LKNAR AMADA LLERG YSLVS GGTDN HLVLV DLRPK GLDGA RAERV LELVS ITANK NTCPG DRSAI TPGGL RLGAP ALTSR QFRED DFRRV VDFID EGVNI GLEVK SKTAK LQDFK SFLLK DSETS QRLAN LRQRV EQFAR AFPMP GFDEH |
| Synonyms: | GLYA, SHMT, mSHMT, NEDCASB, HEL-S-51e |
| Calculated MW: | 56kDa |
| Observed MW: | 56kDa |
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