Description
system_update_alt Datasheet
Product Name: | SETD7 Antibody |
Product Sku: | CPAB0125 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human SETD7 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SETD7 amino acids 1-366 purified from Ecoli. |
Clone: | Ps4E5AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | SETD7 antibody was purified from hybridoma cell supernatant by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | Set 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase. |
Synonyms: | Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, EC 2.1.1.43, Histone H3-K4 methyltransferase, H3-K4-HMTase, SET domain-containing protein 7, Set9, SET7/9, SETD7. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |