Description
| Antibody Name: | Serpinh1 Antibody (PACO29852) | 
| Antibody SKU: | PACO29852 | 
| Size: | 50ug | 
| Host Species: | Rabbit | 
| Tested Applications: | ELISA, WB | 
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 | 
| Species Reactivity: | Mouse, Human | 
| Immunogen: | Recombinant Mouse Serpin H1 protein (18-417AA) | 
| Form: | Liquid | 
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | 
| Purification Method: | >95%, Protein G purified | 
| Clonality: | Polyclonal | 
| Isotype: | IgG | 
| Conjugate: | Non-conjugated | 
|  | Western blot All lanes: Serpinh1 antibody at 6µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa . | 
| Background: | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. | 
| Synonyms: | Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6), Serpinh1, Cbp1 Hsp47 | 
| UniProt Protein Function: | SERPINH1: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. Defects in SERPINH1 are the cause of osteogenesis imperfecta type 10 (OI10). A connective tissue disorder characterized by bone fragility, low bone mass, bowing of limbs due to multiple fractures, short limb dwarfism and blue sclerae. Belongs to the serpin family.Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartmentMolecular Function: serine-type endopeptidase inhibitor activity; collagen binding; protein binding; unfolded protein bindingBiological Process: collagen fibril organization; protein maturation; collagen biosynthetic process | 
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P19324 | 
| NCBI GenInfo Identifier: | 161353504 | 
| NCBI Gene ID: | 12406 | 
| NCBI Accession: | NP_001104513.1 | 
| UniProt Secondary Accession: | P19324,Q5U4D0 | 
| UniProt Related Accession: | P19324 | 
| Molecular Weight: | |
| NCBI Full Name: | serpin H1 | 
| NCBI Synonym Full Names: | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 
| NCBI Official Symbol: | Serpinh1 | 
| NCBI Official Synonym Symbols: | J6; Cbp1; Cbp2; gp46; Hsp47; BERF-1; Serpinh2 | 
| NCBI Protein Information: | serpin H1 | 
| UniProt Protein Name: | Serpin H1 | 
| UniProt Synonym Protein Names: | 47 kDa heat shock protein; Collagen-binding protein; Colligin; Serine protease inhibitor J6 | 
| Protein Family: | |
| UniProt Gene Name: | Serpinh1 | 
| UniProt Entry Name: | SERPH_MOUSE | 
 
 
             
             
             
             
            