Description
Antibody Name: | Serpinh1 Antibody (PACO29852) |
Antibody SKU: | PACO29852 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Mouse, Human |
Immunogen: | Recombinant Mouse Serpin H1 protein (18-417AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: Serpinh1 antibody at 6µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa . |
Background: | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. |
Synonyms: | Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6), Serpinh1, Cbp1 Hsp47 |
UniProt Protein Function: | SERPINH1: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. Defects in SERPINH1 are the cause of osteogenesis imperfecta type 10 (OI10). A connective tissue disorder characterized by bone fragility, low bone mass, bowing of limbs due to multiple fractures, short limb dwarfism and blue sclerae. Belongs to the serpin family.Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartmentMolecular Function: serine-type endopeptidase inhibitor activity; collagen binding; protein binding; unfolded protein bindingBiological Process: collagen fibril organization; protein maturation; collagen biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P19324 |
NCBI GenInfo Identifier: | 161353504 |
NCBI Gene ID: | 12406 |
NCBI Accession: | NP_001104513.1 |
UniProt Secondary Accession: | P19324,Q5U4D0 |
UniProt Related Accession: | P19324 |
Molecular Weight: | |
NCBI Full Name: | serpin H1 |
NCBI Synonym Full Names: | serine (or cysteine) peptidase inhibitor, clade H, member 1 |
NCBI Official Symbol: | Serpinh1 |
NCBI Official Synonym Symbols: | J6; Cbp1; Cbp2; gp46; Hsp47; BERF-1; Serpinh2 |
NCBI Protein Information: | serpin H1 |
UniProt Protein Name: | Serpin H1 |
UniProt Synonym Protein Names: | 47 kDa heat shock protein; Collagen-binding protein; Colligin; Serine protease inhibitor J6 |
Protein Family: | |
UniProt Gene Name: | Serpinh1 |
UniProt Entry Name: | SERPH_MOUSE |