SEC61B Polyclonal Antibody
- SKU:
- CAB21807
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | SEC61B Polyclonal Antibody |
| Product Code: | CAB21807 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Single-pass membrane protein |
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-96 of human SEC61B (NP_006799.1). |
| Sequence: | MPGPT PSGTN VGSSG RSPSK AVAAR AAGST VRQRK NASCG TRSAG RTTSA GTGGM WRFYT EDSPG LKVGP VPVLV MSLLF IASVF MLHIW GKYTR S |
| Synonyms: | SEC61B, Sec61 translocon beta subunit |
| Calculated MW: | 10kDa |
| Observed MW: | Refer to figures |
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