SDHC Monoclonal Antibody
- SKU:
- CAB22280
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | SDHC Monoclonal Antibody |
| Product Code: | CAB22280 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55260 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, HeLa, Mouse kidney, Rat liver, Rat heart |
| Cellular Location: | Mitochondrion inner membrane, Multi-pass membrane protein |
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SDHC (NP_002992.1). |
| Sequence: | MAALL LRHVG RHCLR AHFSP QLCIR NAVPL GTTAK EEMER FWNKN IGSNR PLSPH ITIYS WSLPM AMSIC HRGTG IALSA GVSLF GMSAL LLPGN FESYL |
| Synonyms: | CYBL, PGL3, QPS1, SDH3, CYB560 |
| Calculated MW: | 19kDa |
| Observed MW: | 12kDa |
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