Description
system_update_alt Datasheet
Product Name: | SAR1B Antibody |
Product Sku: | CPAB0494 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human SAR1B mAb, clone PAT1C7A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MRRF protein 1-198 amino acids purified from Ecoli. |
Clone: | PAT1C7A. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | SAR1B antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | SAR1B is a small GTPase that functions as a homodimer. GTP-Binding Protein SAR1B (SAR1b) is involved in transport from the endoplasmic reticulum to the Golgi apparatus and also in the selection of the protein cargo and the assembly of the COPII coat complex. The SAR1B protein is activated by the guanine nucleotide exchange factor PREB. SAR1B gene defects are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). |
Synonyms: | GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB, ANDD, CMRD. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |