Description
Product Name: | RNPC3 Polyclonal Antibody |
Product Code: | CAB11970 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Nucleus |
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RNPC3 (NP_060089.1). |
Sequence: | MAAPE QPLAI SRGCT SSSSL SPPRG DRTLL VRHLP AELTA EEKED LLKYF GAQSV RVLSD KGRLK HTAFA TFPNE KAAIK ALTRL HQLKL LGHTL VVEFA |
Synonyms: | RNP, CPHD7, IGHD5, RBM40, SNRNP65 |
Calculated MW: | 59kDa |
Observed MW: | Refer to figures |