Rhesus macaque IL-33 Recombinant Protein (RPES3749)
- SKU:
- RPES3749
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Frequently bought together:
Description
system_update_altDatasheet
Rhesus macaque IL-33 Recombinant Protein
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-?B and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
| Product Name: | Rhesus macaque IL-33 Recombinant Protein (RPES3749) |
| Product Code: | RPES3749 |
| Size: | 10µg |
| Species: | Rhesus macaque |
| Expressed Host: | E.coli |
| Synonyms: | Interleukin-33, IL-33, Interleukin-1 Family Member 11, IL-1F11, Nuclear Factor From High Endothelial Venules, NF-HEV, IL33, C9orf26, IL1F11, NFHEV |
| Accession: | F7DLG4 |
| Sequence: | Ser112-Ile270 |
| Fusion tag: | N-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Rhesus macaque Interleukin 33 is produced by our E.coli expression system and the target gene encoding Ser112-Ile270 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 20.3 kDa |
| AP Mol Mass: | 21 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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