REV3L Polyclonal Antibody
- SKU:
- CAB10675
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | REV3L Polyclonal Antibody |
| Product Code: | CAB10675 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Nucleus |
| Customer Validation: | WB(Homo sapiens) |
The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-500 of human REV3L (NP_002903.3). |
| Sequence: | PSSLI LEGVE PQSTC ELEVD AVAAD ILNRL DIEAQ IGGNP GLQAI WEDEK QRRRN RNETS QMSQP ESQDH RFVPA TESEK KFQKR LQEIL KQNDF SVTLS GSVDY SDGSQ EFSAE LTLHS EVLSP EMLQC TPANM VEVHK DKESS KGHTR HKVEE ALINE EAILN LMENS QTFQP LTQRL SESPV FMDSS PDEAL VHLLA GLESD GYRGE RNRMP SPCRS FGNNK YPQNS DDEEN EPQIE KEEME LSLVM SQRWD SNIEE HCAKK RSLCR NTHRS STEDD D |
| Synonyms: | POLZ, REV3 |
| Calculated MW: | 353kDa |
| Observed MW: | Refer to figures |
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