RECQL Polyclonal Antibody
- SKU:
- CAB10676
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | RECQL Polyclonal Antibody |
| Product Code: | CAB10676 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Nucleus |
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-649 of human RECQL (NP_116559.1). |
| Sequence: | QESGR AGRDD MKADC ILYYG FGDIF RISSM VVMEN VGQQK LYEMV SYCQN ISKCR RVLMA QHFDE VWNSE ACNKM CDNCC KDSAF ERKNI TEYCR DLIKI LKQAE ELNEK LTPLK LIDSW MGKGA AKLRV AGVVA PTLPR EDLEK IIAHF LIQQY LKEDY SFTAY ATISY LKIGP KANLL NNEAH AITMQ VTKST QNSFR AESSQ TCHSE QGDKK MEEKN SGNFQ KKAAN MLQQS GSKNT GAKKR KIDDA |
| Synonyms: | RecQ1, RECQL1 |
| Calculated MW: | 73kDa |
| Observed MW: | Refer to figures |
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