Name: Recombinant SARS-CoV Plpro/papain-like protease (His Tag)
SKU: RPES6869
Availability: OutOfStock

Recombinant SARS-CoV Plpro/papain-like protease (His Tag)

(No reviews yet) Write a Review

SKU:

RPES6869

Product Type:

Recombinant Protein

Species:

Virus

Description

View AllClose

0 Reviews

View AllClose

OverviewProduct Name:SARS-Cov-2 Papain-Like Protease Recombinant ProteinProduct Code:RPES0008Size:10µgSynonyms:Papain-like Protea

OverviewProduct Name:SARS-CoV S1 Recombinant Protein (His Tag)（Active）Product Code:RPES6868Size:100µgSpecies:SARS

OverviewProduct Name:SARS-CoV S1 Recombinant Protein, Biotinylated (His Tag)Product Code:RPES6870Size:20µgSpecies:SARS<

OverviewProduct Name:Recombinant SARS-CoV-2 Spike RBD (F377L) (His Tag)Product Code:RPES7150Size:100µgSpecies:SARS-CoV-2

Mol Mass:	36.65kDa.
Tag:	C-His
Purity:	> 90 % as determined by reducing SDS-PAGE.
Endotoxin Level:	Please contact us for more information.
Bio Activity:	Testing in progress

Sequence:	Glu1541-Tyr1859
Accession:	AAX16193.1
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from sterile 50 mM Tris, 0.1 % Tween, pH 9.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.