Recombinant Rabbit IL1B protein (His tag) (RPES9100)

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SKU:
RPES9100
Product Type:
Protein
Size:
20μg, 100μg, 500μg, 1mg
Tag:
N-His
Expression Host:
E.coli
Host Species:
Rabbit
Application Area:
Cytokines & Chemokines
Frequently bought together:

Description

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Recombinant Rabbit IL1B Protein(His Tag) (RPES9100)

Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

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