Immune Checkpoint

Human OX40 Recombinant Protein (hFc-His Tag)Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5...

Human OX40L Recombinant Protein (mFc-His Tag)Description:This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated...

Human GITR Ligand Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to...

Human GITR Recombinant Protein (mFc-His Tag)Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant...

Human GITR Recombinant Protein (hFc-His Tag)Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant...

Human CTLA-4 Recombinant Protein (mFc-His Tag)Description:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a...

Human CD48 Recombinant Protein (mFc-His Tag)Description:This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface...

Human CD40 Recombinant Protein (mFc-His Tag)Description:This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and...

Human CD28 Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding...

Human CD27 Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and...

Human B7-H3 Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript...

Human 4-1BB Recombinant Protein (mFc-His Tag)Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce...