Recombinant Human IL-7 Receptor Subunit alpha/IL-7RA/CD127 (C-6His) (RPES6294)

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SKU:
RPES6294
Product Type:
Recombinant Protein
Species:
Human
Application Area:
Cytokines & Chemokines
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Description

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Product Name:Recombinant Human IL-7 Receptor Subunit alpha/IL-7RA/CD127 (C-6His)
Product Code:RPES6294
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:Interleukin-7 receptor subunit alpha, IL7R, IL-7R-alpha, CD127
Mol Mass:25.7 kDa
AP Mol Mass:40-55 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Glu21-Gly236
Accession:P16871
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
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