Recombinant Human Galectin-9/LGALS9 (N-GST) (RPES6250)

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SKU:
RPES6250
Product Type:
Recombinant Protein
Species:
Human
Application Area:
Immune Receptors
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Description

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Product Name:Recombinant Human Galectin-9/LGALS9 (N-GST)
Product Code:RPES6250
Size:10µg
Species:Human
Expression Host:E.coli
Synonyms:Galectin-9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, LGALS9, Gal-9delta5
Mol Mass:62.2 kDa
AP Mol Mass:60 kDa
Tag:N-GST
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Met1-Thr322
Accession:O00182-2
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation:Supplied as a 0.2 μm filtered solution of 1M PBS, 100 mM GSH, 1% Tritonx-100, 15% Glycerol, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer inform
Reconstitution:Not Applicable
Background:Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1
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