Recombinant Human Carbonic Anhydrase IX/CA9 (C-Avi-6His) Biotinylated (RPES6214)

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SKU:
RPES6214
Product Type:
Recombinant Protein
Species:
Human
Application Area:
Metabolic & Housekeeping Proteins
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Description

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Product Name:Recombinant Human Carbonic Anhydrase IX/CA9 (C-Avi-6His) Biotinylated
Product Code:RPES6214
Size:20µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:CA9, CA-IX, Carbonic Anhydrase IX, Carbonate dehydratase IX, G250, MN, P54/58N, RCC, RCC-associated protein G250
Mol Mass:43.6 kDa
AP Mol Mass:60 kDa
Tag:C-Avi-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Gln38-Asp414
Accession:Q16790
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
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