Rat RAB7A/Rab-7a Recombinant Protein (RPES3277)

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SKU:
RPES3277
Product Type:
Recombinant Protein
Species:
Rat
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Description

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Rat RAB7A/Rab-7a Recombinant Protein

RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. In addition, disease-causing RAB7A mutant proteins bind more strongly to peripherin and their expression causes a significant increase in the amount of soluble peripherin. The altered interaction between disease-causing RAB7A mutants and peripherin could play an important role in CMT2B neuropathy.

Product Name:Rat RAB7A/Rab-7a Recombinant Protein (RPES3277)
Product Code:RPES3277
Size:20µg
Species:Rat
Expressed Host:E. coli
Synonyms:Rab7
Accession:NP_076440.1
Sequence:Met1-Cys207
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the rat Rab7a (NP_076440.1) (Met1-Cys207) was expressed with a polyhistidine tag at the N-terminus.
Purity:> 90 % as determined by SDS-PAGE
Mol Mass:25.7 kDa
Formulation:Lyophilized from sterile PBS, 10 % glycerol
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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