Raptor Polyclonal Antibody (CAB21756)
- SKU:
- CAB21756
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Raptor Polyclonal Antibody |
| Product Code: | CAB21756 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Mouse brain, Rat brain |
| Cellular Location: | Cytoplasm, Cytoplasmic granule, Lysosome |
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 888-1013 of human Raptor (NP_065812.1). |
| Sequence: | LTNDV AKQPV SRDLP SGRPG TTGPA GAQYT PHSHQ FPRTR KMFDK GPEQT ADDAD DAAGH KSFIS ATVQT GFCDW SARYF AQPVM KIPEE HDLES QIRKE REWRF LRNSR VRRQA QQVIQ KGITR L |
| Synonyms: | KOG1, Mip1 |
| Calculated MW: | 149kDa |
| Observed MW: | 150kDa |
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