PU.1/SPI1 Monoclonal Antibody
- SKU:
- CAB24910
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | PU.1/SPI1 Monoclonal Antibody |
| Product Code: | CAB24910 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63111 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, FC, FC(Intra), ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, FC(Intra) 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Daudi |
| Cellular Location: | nucleoplasm, nucleus |
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PU.1/SPI1 (NP_003111.2) |
| Sequence: | MLQAC KMEGF PLVPP PSEDL VPYDT DLYQR QTHEY YPYLS SDGES HSDHY WDFHP HHVHS EFESF AENNF TELQS VQPPQ LQQLY RHMEL EQMHV LDTPM |
| Synonyms: | OF, PU.1, AGM10, SFPI1, SPI-1, SPI-A |
| Calculated MW: | 31kDa |
| Observed MW: | 38kDa |
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