Name: PPRC1 Antibody (PACO03686)
SKU: PACO03686
Availability: OutOfStock

Antibody Name:	PPRC1 Antibody
Antibody SKU:	PACO03686
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	IHC:1:100-1:300
Species Reactivity:	Human, Mouse
Immunogen:	synthesized peptide derived from the C-terminal region of human PRC.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

PPRC1; KIAA0595; Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; PGC-1-related coactivator; PRC

UniProt Protein Function:	PPRC1: Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 10q24.32 Cellular Component: nucleoplasm; nucleus Molecular Function:ligand-dependent nuclear receptor transcription coactivator activity; transcription factor binding Biological Process: mitochondrion organization and biogenesis; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter
NCBI Summary:	The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Code:	Q5VV67
NCBI GenInfo Identifier:	74756889
NCBI Gene ID:	23082
NCBI Accession:	Q5VV67.1
UniProt Secondary Accession:	Q5VV67,Q5VV66, Q6P3U5, Q6P3W1, Q76N31, Q9BUJ3, Q9BZE5 Q9Y4E0,
UniProt Related Accession:	Q5VV67
Molecular Weight:	164,965 Da
NCBI Full Name:	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
NCBI Synonym Full Names:	peroxisome proliferator-activated receptor gamma, coactivator-related 1
NCBI Official Symbol:	PPRC1
NCBI Official Synonym Symbols:	PRC
NCBI Protein Information:	peroxisome proliferator-activated receptor gamma coactivator-related protein 1
UniProt Protein Name:	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
UniProt Synonym Protein Names:	PGC-1-related coactivator; PRC
Protein Family:	Peroxisome proliferator-activated receptor gamma coactivator-related protein
UniProt Gene Name:	PPRC1
UniProt Entry Name:	PPRC1_HUMAN