PPME1 Monoclonal Antibody [PAT29G3AT] (CPAB0251)
![PPME1 Monoclonal Antibody [PAT29G3AT] (CPAB0251)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58476/63658/ppme1-monoclonal-antibody-pat29g3at-cpab0251__69605__77819.1706535025.jpg?c=1 "PPME1 Monoclonal Antibody [PAT29G3AT] (CPAB0251)")
- SKU:
- CPAB0251
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT29G3AT
- Applications:
- WB
- Applications:
- ELISA
![PPME1 Monoclonal Antibody [PAT29G3AT] (CPAB0251)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58476/63658/ppme1-monoclonal-antibody-pat29g3at-cpab0251__69605__77819.1706535025.jpg?c=1&imbypass=on "PPME1 Monoclonal Antibody [PAT29G3AT] (CPAB0251)")
Description
system_update_alt Datasheet
| Product Name: | PPME1 Antibody |
| Product Sku: | CPAB0251 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PPME1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPME1 amino acids 1-386 purified from Ecoli. |
| Clone: | PAT29G3AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | PPME1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | PPME1 catalyzes the demethylation and inactivation of protein phosphatase (PP2A), a multimeric phosphoserine/ threonine protein phosphatase related to growth inhibition and cell cycle arrest. PPME1 can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment can inhibit this reaction. It is conserved from yeast to human and holds a motif found in lipases having a catalytic triad activated serine as their active site nucleophile. |
| Synonyms: | Protein phosphatase methylesterase 1, PME-1, FLJ22226, EC 3.1.1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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