PP2A-B55α/PR55α/PPP2R2A Monoclonal Antibody
- SKU:
- CAB24261
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PP2A-B55α/PR55α/PPP2R2A Monoclonal Antibody |
| Product Code: | CAB24261 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60262 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | cytosol, glutamatergic synapse, nucleoplasm |
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 94-194 of human PP2A-B55α/PR55α/PPP2R2A (NP_002708.1). |
| Sequence: | EKINK IRWLP QKNAA QFLLS TNDKT IKLWK ISERD KRPEG YNLKE EDGRY RDPTT VTTLR VPVFR PMDLM VEASP RRIFA NAHTY HINSI SINSD YETYL S |
| Synonyms: | B55A, PR52A, PR55A, B55ALPHA, PR55alpha |
| Calculated MW: | 52kDa |
| Observed MW: | 52kDa |
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