PP2A-Aβ/PR65β/PPP2R1B Polyclonal Antibody (CAB21559)
- SKU:
- CAB21559
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | PP2A-Aβ/PR65β/PPP2R1B Polyclonal Antibody |
| Product Code: | CAB21559 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | hek293T |
| Cellular Location: | cytoplasm, extracellular exosome |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 468-667 of human PP2A-Aβ/PR65β/PPP2R1B (NP_859050.1). |
| Sequence: | YAIRE AATNN LMKLV QKFGT EWAQN TIVPK VLVMA NDPNY LHRMT TLFCI NALSE ACGQE ITTKQ MLPIV LKMAG DQVAN VRFNV AKSLQ KIGPI LDTNA LQGEV KPVLQ KLGQD EDMDV KYFAQ EAISV VAQRL RKLEF PVKDS GEPSV PRADK NHFPR PTVPG EDMGK GPVYQ LRGDT RDTLA QLGIA ELVHF SQSTD |
| Synonyms: | PR65B, PP2A-Abeta |
| Calculated MW: | 66kDa |
| Observed MW: | 66kDa |
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