PMPCA Monoclonal Antibody
- SKU:
- CAB24606
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IP
Description
| Product Name: | PMPCA Monoclonal Antibody |
| Product Code: | CAB24606 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63472 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500, IP 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, MCF7, Mouse placenta, Rat thymus |
| Cellular Location: | Mitochondrion matrix, Mitochondrion inner membrane |
The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 291-525 of human PMPCA (NP_055975.1). |
| Sequence: | AQYTG GIAKL ERDMS NVSLG PTPIP ELTHI MVGLE SCSFL EEDFI PFAVL NMMMG GGGSF SAGGP GKGMF SRLYL NVLNR HHWMY NATSY HHSYE DTGLL CIHAS ADPRQ VREMV EIITK EFILM GGTVD TVELE RAKTQ LTSML MMNLE SRPVI FEDVG RQVLA TRSRK LPHEL CTLIR NVKPE DVKRV ASKML RGKPA VAALG DLTDL PTYEH IQTAL SSKDG RLPRT YRLFR |
| Synonyms: | CLA1, CPD3, MAS2, P-55, SCAR2, INPP5E, Alpha-MPP |
| Calculated MW: | 55kDa |
| Observed MW: | 58kDa |
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