PMEL Monoclonal Antibody
- SKU:
- CAB23684
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | PMEL Monoclonal Antibody |
| Product Code: | CAB23684 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59527 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | SK-MEL-28 cells |
| Cellular Location: | Cytoplasm, Endoplasmic reticulum membrane, Endosome, Golgi apparatus, Melanosome, Secreted, Single-pass type I membrane protein, multivesicular body |
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
| Immunogen: | Recombinant protein of human PMEL |
| Sequence: | Email for sequence |
| Synonyms: | P1, SI, SIL, ME20, P100, SILV, HMB45, ME20M, gp100, HMB-45, ME20-M, PMEL17, D12S53E |
| Calculated MW: | 70kDa |
| Observed MW: | 100kDa |
Related Products
Anti-PMEL Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0264)
system_update_altDatasheetOverviewSKU:
Anti-PMEL Antibody (CAB5384)
OverviewProduct Name:PMEL Rabbit pAbProduct Code:CAB5384Size:20uL, 50uL, 100uLSynonyms:PMEL, D12S53E, ME20, ME20-M, ME20M, P1, P100, PME
