Description
| Product Name: | PLZF Monoclonal Antibody |
| Product Code: | CAB21185 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52265 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, Mouse heart, Rat brain |
| Cellular Location: | Nucleus |
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-300 of human PLZF (NP_005997.2). |
| Sequence: | TKAAV DSLMT IGQSL LQGTL QPPAG PEEPT LAGGG RHPGV AEVKT EMMQV DEVPS QDSPG AAESS ISGGM GDKVE ERGKE GPGTP TRSSV ITSAR ELHYG RE |
| Synonyms: | PLZF, ZNF145 |
| Calculated MW: | 74kDa |
| Observed MW: | 80kDa |