Description
| Product Name: | PLPP3 Monoclonal Antibody |
| Product Code: | CAB24734 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63237 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, Mouse brain, Mouse uterus, Rat uterus |
| Cellular Location: | Cell membrane, Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane |
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLPP3(NP_003704.3). |
| Sequence: | MQNYK YDKAI VPESK NGGSP ALNNN PRRSG SKRVL LICLD LFCLF MAGLP FLIIE TSTIK PYHRG FYCND ESIKY PLKTG ETIND AVLCA VGIVI AILAI |
| Synonyms: | LPP3, VCIP, Dri42, PAP2B, PPAP2B |
| Calculated MW: | 35kDa |
| Observed MW: | 35kDa |