PLOD3 Monoclonal Antibody (CAB22354)
- SKU:
- CAB22354
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | PLOD3 Monoclonal Antibody |
| Product Code: | CAB22354 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52018 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, BxPC-3, HepG2, Jurkat(Low expression control) |
| Cellular Location: | Lumenal side, Peripheral membrane protein, Rough endoplasmic reticulum membrane |
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-306 of human PLOD3 (NP_001075.1). |
| Sequence: | SDRPR GRDPV NPEKL LVITV ATAET EGYLR FLRSA EFFNY TVRTL GLGEE WRGGD VARTV GGGQK VRWLK KEMEK YADRE DMIIM FVDSY DVILA GSPTE LLKKF VQSGS RLLFS AESFC WPEWG LAEQY PEVGT GKRFL NSGGF IGFAT TIHQI VRQWK YKDDD DDQLF YTRLY LDPGL REKLS LNLDH KSRIF QNLNG ALDEV VLKFD RNRVR IRNVA YDTLP IVVHG NGPTK LQLNY LGNYV PNGWT PEGGC GFCNQ DRRTL PGGQP PPRVF LAVFV EQ |
| Synonyms: | LH3 |
| Calculated MW: | 85kDa |
| Observed MW: | 80kDa |
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